Editorial Reviews
Product Description
Product Details
- Paperback: 176 pages
- Publisher: Vault, Inc. (May 25, 2006)
- Language: English
- ISBN-10: 1581313896
- ISBN-13: 978-1581313895
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Biomedical Engineering: Bridging Medicine and Technology
Organic Electronics in Sensors and Biotechnology 2009

Book Description
The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with ‘newer’ pharmaceutical substances derived from genetic engineering or hybridoma technology.
This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
Table of Contents
Preface
Ch. 1 Pharmaceuticals, biologics and biopharmaceuticals 1
Ch. 2 The drug development process 43
Ch. 3 The drug manufacturing process 93
Ch. 4 The cyotkines – the interferon family 189
Ch. 5 Cytokines: interleukins and tumour necrosis factor 223
Ch. 6 Haemopoietic growth factors 255
Ch. 7 Growth factors 277
Ch. 8 Hormones of therapeutic interest 303
Ch. 9 Blood products and therapeutic enzymes 351
Ch. 10 Antibodies, vaccines and adjuvants 403
Ch. 11 Nucleic acid therapeutics 463
App. 1 Biopharmaceuticals thus far approved in the USA or European Union 499
App. 2 Some Internet addresses relevant to the biopharmaceutical sector 509
App. 3 Two selected monographs reproduced from the European Pharmacopoeia (Products of recombinant DNA technology; Interferon a-2 concentrated solution) 515
App. 4 Manufacture of biological medicinal products for human use 527
Index 533

Publisher: Wiley-Interscience
Number Of Pages:
Publication Date: 2007-06-11
Sales Rank: 1432526
ISBN / ASIN: 0471213861
EAN: 9780471213864
Binding: Hardcover
Manufacturer: Wiley-Interscience
Studio: Wiley-Interscience
A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs
The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process
from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas,
this reference:
Provides an overview of biotechnology used in the drug development process
Covers extensive applications, plus regulations and validation methods
Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics
With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers,
toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality


Advances in Bioactivation Research (Biotechnology: Pharmaceutical Aspects)
By Adnan Elfarra
Publisher: Springer
Number Of Pages: 504
Publication Date: 2008-09-19
ISBN-10 / ASIN: 0387772995
ISBN-13 / EAN: 9780387772998
Product Description:
This volume will provide researchers with recent information on bioactivation reactions of drugs and toxicants and will provide examples of how molecular and genomic biology, proteomics, mass spectrometry, and computational modeling are used in bioactivation research. In other sections of this volume, focus will be on recent applications of bioactivation research in pharmacology, toxicology, and environmental health sciences. In these sections, the contributors will demonstrate the integration of bioactivation research in several research areas, including new drug design, drug development, mechanisms of cell death, toxicity and carcinogenicity, metabolite-specific biomarkers of exposure and effect, and extrapolations of results from animal models to humans.
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